Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function

Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function

•MHC class I alleles vary in their intrinsic ability to select optimal peptides.•Ability of MHC to self-assemble is inversely correlated with dependence on tapasin.•Variation in peptide selector function correlates with the plasticity of empty MHC.•Increased plasticity of empty MHC I allows more eff...

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Bibliographic Details
Main Authors: van Hateren, Andy, Bailey, Alistair, Werner, Jörn M., Elliott, Tim
Format: Online
Language:English
Published: Pergamon Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726658/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726658/

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