Mechanisms Restricting Diffusion of Intracellular cAMP

Although numerous receptors stimulate cAMP production in a wide array of cells, many elicit distinct, highly localized responses, implying that the subcellular distribution of cAMP is not uniform. One often used explanation is that phosphodiesterases, which breakdown cAMP, act as functional barriers...

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Bibliographic Details
Main Authors: Agarwal, Shailesh R., Clancy, Colleen E., Harvey, Robert D.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726171/