Adjuvant bisphosphonate treatment for breast cancer: Where are we heading and can the pre-clinical literature help us get there?

Bisphosphonates have demonstrated anti-tumour activity in preclinical studies of bone metastatic disease, thus it was natural to transition these agents into the adjuvant cancer therapy setting. Surprisingly, the results of adjuvant breast cancer trials have shown either modest to no benefit or even...

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Bibliographic Details
Main Authors: Russell, Kent, Clemons, Mark, Costa, Luis, Addison, Christina L.
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723323/