Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway

Studies have indicated that trichosanthin (TCS), a bioactive protein extracted and purified from the tuberous root of Trichosanthes kirilowii (a well-known traditional Chinese medicinal plant), produces antitumor effects on various types of cancer cells. However, the effects of TCS on glioma cells a...

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Bibliographic Details
Main Authors: MIAO, JUNJIE, JIANG, YILIN, WANG, DONGLIANG, ZHOU, JINGRU, FAN, CUNGANG, JIAO, FENG, LIU, BO, ZHANG, JUN, WANG, YANGSHUO, ZHANG, QINGJUN
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722885/