Pilot experience with opebacan/rBPI 21 in myeloablative hematopoietic cell transplantation

Bacterial infection and inflammation contribute significantly to the morbidity and mortality of myeloablative allogeneic hematopoietic cell transplantation (HCT). Endotoxin, a component of the outer membrane of Gram-negative bacteria, is a potent inflammatory stimulus in humans. Bactericidal/permeab...

Full description

Bibliographic Details
Main Authors: Guinan, Eva, Avigan, David E, Soiffer, Robert J, Bunin, Nancy J, Brennan, Lisa L, Bergelson, Ilana, Brightman, Spencer, Ozonoff, Al, Scannon, Patrick J, Levy, Ofer
Format: Online
Language:English
Published: F1000Research 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722698/