Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice

Adult hippocampal dentate granule neurons are generated from neural stem cells (NSCs) in the mammalian brain, and the fate specification of adult NSCs is precisely controlled by the local niches and environment, such as the subventricular zone (SVZ), dentate gyrus (DG), and Toll-like receptors (TLRs...

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Bibliographic Details
Main Authors: Seong, Kyung-Joo, Lee, Hyun-Gwan, Kook, Min Suk, Ko, Hyun-Mi, Jung, Ji-Yeon, Kim, Won-Jae
Format: Online
Language:English
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722190/