The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis

Neurochemical biomarkers are urgently sought in ALS. Metabolomic analysis of cerebrospinal fluid (CSF) using proton nuclear magnetic resonance (1H-NMR) spectroscopy is a highly sensitive method capable of revealing nervous system cellular pathology. The 1H-NMR CSF metabolomic signature of ALS was so...

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Bibliographic Details
Main Authors: Gray, Elizabeth, Larkin, James R., Claridge, Tim D. W., Talbot, Kevin, Sibson, Nicola R., Turner, Martin R.
Format: Online
Language:English
Published: Informa Healthcare 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720042/