Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies

Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies

The homeobox protein, PEPP2 (RHOXF2), has been suggested as a cancer/testis (CT) antigen based on its expression pattern. However, the peptide epitope of PEPP2 that is recognized by cytotoxic T cells (CTLs) is unknown. In this study, we revealed that PEPP2 gene was highly expressed in myeloid leukem...

Full description

Bibliographic Details
Main Authors: Matsushita, Maiko, Otsuka, Yohei, Tsutsumida, Naoya, Tanaka, Chiaki, Uchiumi, Akane, Ozawa, Koji, Suzuki, Takuma, Ichikawa, Daiju, Aburatani, Hiroyuki, Okamoto, Shinichiro, Kawakami, Yutaka, Hattori, Yutaka
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718592/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718592/

Similar Items