Dual use of GTP hydrolysis by elongation factor G on the ribosome
Elongation factor G (EF-G) is a GTPase that catalyzes tRNA and mRNA translocation during the elongation cycle of protein synthesis. The GTP-bound state of the factor on the ribosome has been studied mainly with non-hydrolyzable analogs of GTP, which led to controversial conclusions about the role of...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718068/ |