The human rs1050286 polymorphism alters LOX‐1 expression through modifying miR‐24 binding

The human rs1050286 polymorphism alters LOX‐1 expression through modifying miR‐24 binding

The up‐regulation of lectin‐like oxidized low‐density lipoprotein receptor‐1 (LOX‐1), encoded by the OLR1 gene, plays a fundamental role in the pathogenesis of atherosclerosis. Moreover, OLR1 polymorphisms were associated with increased susceptibility to acute myocardial infarction (AMI) and coronar...

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Bibliographic Details
Main Authors: Morini, Elena, Rizzacasa, Barbara, Pucci, Sabina, Polidoro, Chiara, Ferrè, Fabrizio, Caporossi, Daniela, Helmer Citterich, Manuela, Novelli, Giuseppe, Amati, Francesca
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717858/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717858/

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