Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells

Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells

Transforming growth factor β (TGFβ) causes the acquisition of epithelial–mesenchymal transition (EMT). Although the tumor suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) can negatively regulate many signaling pathways activated by TGFβ, hyperactivation of these sig...

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Bibliographic Details
Main Authors: Kusunose, Masaaki, Hashimoto, Naozumi, Kimura, Motohiro, Ogata, Ryo, Aoyama, Daisuke, Sakamoto, Koji, Miyazaki, Shinichi, Ando, Akira, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714667/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714667/

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