Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial

Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial

Bibliographic Details
Main Authors:	Reichardt, Peter, Demetri, George D., Gelderblom, Hans, Rutkowski, Piotr, Im, Seock-Ah, Gupta, Sudeep, Kang, Yoon-Koo, Schöffski, Patrick, Schuette, Jochen, Soulières, Denis, Blay, Jean-Yves, Goldstein, David, Fly, Kolette, Huang, Xin, Corsaro, Massimo, Lechuga, Maria Jose, Martini, Jean-Francois, Heinrich, Michael C.
Format:	Online
Language:	English
Published:	BioMed Central 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714485/

Similar Items

Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors
by: Gao, Jing, et al.
Published: (2016)

Malignant melanoma of the conjunctiva: a case report with examination of KIT and PDGFRA
by: Terada, Tadashi
Published: (2012)

Small cell carcinoma of the urinary bladder: KIT and PDGFRA gene mutations
by: Nuket Eliyakin, et al.
Published: (2015-12-01)

Malignant melanoma of the conjunctiva: a case report with examination of KIT and PDGFRA
by: Tadashi Terada
Published: (2012-01-01)

Malignant melanoma of the conjunctiva: a case report with examination of KIT and PDGFRA
by: Tadashi Terada
Published: (2012-01-01)

Data on quantification of signaling pathways activated by KIT and PDGFRA mutants
by: Bahlawane, Christelle, et al.
Published: (2016)

Small Cell Carcinoma of the Urinary Bladder: KIT and PDGFRA Gene Mutations
by: Eliyakin, Nuket, et al.
Published: (2015)

Response to sunitinib of a gastrointestinal stromal tumor with a rare exon 12 PDGFRA mutation
by: Brohl, Andrew S., et al.
Published: (2015)

Effect of gastrointestinal resection on sunitinib exposure in patients with GIST
by: de Wit, Djoeke, et al.
Published: (2014)

The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting
by: Maleddu, Alessandra, et al.
Published: (2011)

A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT)
by: Petrou, Athanasios, et al.
Published: (2011)

Malignant melanoma of the nasal cavity: a case report with examination of KIT and platelet derived growth factor receptor-α(PDGFRA)
by: Terada, Tadashi
Published: (2011)

Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA
by: Beadling, Carol, et al.
Published: (2013)

Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumors: a meta-analysis
by: Zong, Liang, et al.
Published: (2014)

Molecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1
by: Tefferi, Ayalew
Published: (2009)

Malignant melanoma of the nasal cavity: a case report with examination of KIT and platelet derived growth factor receptor-α (PDGFRA)
by: Tadashi Terada
Published: (2011-10-01)

Erratum to: The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)
by: Margherita Nannini, et al.
Published: (2017-06-01)

The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)
by: Margherita Nannini, et al.
Published: (2017-05-01)

Concomitant KIT/BRAF and PDGFRA/BRAF mutations are rare events in gastrointestinal stromal tumors
by: Rossi, Sabrina, et al.
Published: (2016)

Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or PDGFRA mutations
by: Rizzo, Francesca Maria, et al.
Published: (2016)

Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors
by: Pantaleo, Maria A, et al.
Published: (2014)

Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST)
by: Nannini, Margherita, et al.
Published: (2014)

Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways
by: Pantaleo, Maria A, et al.
Published: (2015)

Clinical activity of regorafenib in PDGFRA-mutated gastrointestinal stromal tumor
by: Grellety, Thomas, et al.
Published: (2015)

Succinate dehydrogenase deficiency in a PDGFRA mutated GIST
by: Martin G. Belinsky, et al.
Published: (2017-08-01)

Efficacy and safety of motesanib, an oral inhibitor of VEGF, PDGF, and Kit receptors, in patients with imatinib-resistant gastrointestinal stromal tumors
by: Benjamin, Robert S., et al.
Published: (2010)

Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma
by: Gore, M E, et al.
Published: (2015)

Efficacy of pazopanib and sunitinib in advanced axial chordoma: a single reference centre case series
by: Lipplaa, Astrid, et al.
Published: (2016)

Soluble KIT correlates with clinical outcome in patients with metastatic breast cancer treated with sunitinib
by: Keyvanjah, Kiana, et al.
Published: (2012)

Expression of DOG1, PDGFRA, and p16 in Gastrointestinal Stromal Tumors
by: Jung, Sung Hee, et al.
Published: (2011)

Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA
by: Chen, Dongfeng, et al.
Published: (2014)

Chronic eosinophilic leukemia with FIP1L1-PDGFRA rearrangement
by: Kim, Tae Hee, et al.
Published: (2016)

Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma
by: Hutson, T E, et al.
Published: (2014)

Sunitinib: the antiangiogenic effects and beyond
by: Hao, Zhonglin, et al.
Published: (2016)

Sunitinib Induced Immune Thrombocytopenia
by: Shekarriz, Ramin, et al.
Published: (2015)

Prognostic factors for survival in 1059 patients treated with sunitinib for metastatic renal cell carcinoma
by: Motzer, R J, et al.
Published: (2013)

Phase I study of sunitinib plus S-1 and cisplatin in Japanese patients with advanced or metastatic gastric cancer
by: Boku, Narikazu, et al.
Published: (2013)

Worldwide
Published: (2002)

Unraveling the Worldwide Pollution Haven Effect
by: Grether, Jean-Marie, et al.
Published: (2012)

Sunitinib for advanced renal cell cancer
by: Coppin, Chris
Published: (2008)