Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex

p300, a ubiquitous transcription coactivator, plays an important role in gene activation. Our previous work demonstrated that human inducible nitric oxide synthase (hiNOS) expression can be highly induced with the cytokine mixture (CM) of TNF-α + IL-1β + IFN-γ. In this study, we investigated the fun...

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Bibliographic Details
Main Authors: Guo, Zhong, Zheng, Liang, Liao, Xinghua, Geller, David
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713468/