Diffusion of GPI-anchored proteins is influenced by the activity of dynamic cortical actin

Membrane proteins that couple to cortical actin show temperature-independent diffusion. The loss of this coupling and perturbation of cortical actomyosin dynamics render the diffusion temperature dependent. The findings suggest that active fluctuations arising from dynamic actin filaments at the cor...

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Bibliographic Details
Main Authors: Saha, Suvrajit, Lee, Il-Hyung, Polley, Anirban, Groves, Jay T., Rao, Madan, Mayor, Satyajit
Format: Online
Language:English
Published: The American Society for Cell Biology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710234/