Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery
Sn2 lipase labile phospholipid prodrugs in conjunction with contact-facilitated drug delivery offer an important advancement in Nanomedicine. Many drugs incorporated into nanosystems, targeted or not, are substantially lost during circulation to the target. However, favorably altering the pharmacoki...
Main Authors: | Pan, Dipanjan, Pham, Christine TN, Weilbaecher, Katherine N, Tomasson, Michael H, Wickline, Samuel A, Lanza, Gregory M |
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Format: | Online |
Language: | English |
Published: |
John Wiley & Sons, Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709477/ |
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