Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes

Design and evaluation of novel interferon lambda analogs with enhanced antiviral activity and improved drug attributes

Type III interferons (IFNs) (also called IFN-λ: IFN-λ1, IFN-λ2, IFN-λ3, and IFN-λ4) are critical players in the defense against viral infection of mucosal epithelial cells, where the activity of type I IFNs is weak, and unlike type I IFNs that are associated with severe and diverse side effects, typ...

Full description

Bibliographic Details
Main Authors: Yu, Debin, Zhao, Mingzhi, Dong, Liwei, Zhao, Lu, Zou, Mingwei, Sun, Hetong, Zhang, Mengying, Liu, Hongyu, Zou, Zhihua
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708225/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708225/

Similar Items