PI3K/Akt/mTOR inhibitors in breast cancer
Activation of the phosphoinositide 3 kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in breast cancer. There is preclinical data to support inhibition of the pathway, and phase I to III trials involving inhibitors of the pathway have been or are being conducted in solid tumo...
Main Authors: | Lee, Joycelyn JX, Loh, Kiley, Yap, Yoon-Sim |
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Format: | Online |
Language: | English |
Published: |
Chinese Anti-Cancer Association
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706528/ |
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