Identification of large-scale genomic variation in cancer genomes using in silico reference models

Identifying large-scale structural variation in cancer genomes continues to be a challenge to researchers. Current methods rely on genome alignments based on a reference that can be a poor fit to highly variant and complex tumor genomes. To address this challenge we developed a method that uses avai...

Full description

Bibliographic Details
Main Authors: Killcoyne, Sarah, del Sol, Antonio
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705683/