Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation

Global mRNA abundance depends on the balance of synthesis and decay of a population of mRNAs. To account for this balance during activation of T cells, we used metabolic labeling to quantify the contributions of RNA transcription and decay over a 4 h time course during activation of leukemia-derived...

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Bibliographic Details
Main Authors: Blackinton, Jeff G., Keene, Jack D.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705648/