Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the mosquito midgut and are widely considered to be an essential tool for malaria elimination. High-titer functional antibodies are required against target antigens to achieve effective transmission-blocking act...

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Bibliographic Details
Main Authors: Li, Yuanyuan, Leneghan, Darren B., Miura, Kazutoyo, Nikolaeva, Daria, Brian, Iona J., Dicks, Matthew D. J., Fyfe, Alex J., Zakutansky, Sarah E., de Cassan, Simone, Long, Carole A., Draper, Simon J., Hill, Adrian V. S., Hill, Fergal, Biswas, Sumi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705524/

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