Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility

Chloroquine (CQ)-resistant Plasmodium vivax is present in most countries where P. vivax infection is endemic, but the underlying molecular mechanisms responsible remain unknown. Increased expression of P. vivax crt-o (pvcrt-o) has been correlated with in vivo CQ resistance in an area with low-grade...

Full description

Bibliographic Details
Main Authors: Pava, Zuleima, Handayuni, Irene, Wirjanata, Grennady, To, Sheren, Trianty, Leily, Noviyanti, Rintis, Poespoprodjo, Jeanne Rini, Auburn, Sarah, Price, Ric N., Marfurt, Jutta
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704153/