Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors

AMPA subtype ionotropic glutamate receptors (iGluRs) mediate the majority of fast neurotransmission across excitatory synapses in the central nervous system. Each AMPA receptor is composed of four multi-domain subunits that are organized into layers of two amino-terminal domain (ATD) dimers, two lig...

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Bibliographic Details
Main Authors: Yelshanskaya, Maria V., Saotome, Kei, Singh, Appu K., Sobolevsky, Alexander I.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703952/