Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine
Genome-scale metabolic models (GEMs) have become a popular tool for systems biology, and they have been used in many fields such as industrial biotechnology and systems medicine. Since more and more studies are being conducted using GEMs, they have recently received considerable attention. In this r...
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| Format: | Online |
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Frontiers Media S.A.
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703781/ |
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pubmed-47037812016-01-15 Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine Zhang, Cheng Hua, Qiang Physiology Genome-scale metabolic models (GEMs) have become a popular tool for systems biology, and they have been used in many fields such as industrial biotechnology and systems medicine. Since more and more studies are being conducted using GEMs, they have recently received considerable attention. In this review, we introduce the basic concept of GEMs and provide an overview of their applications in biotechnology, systems medicine, and some other fields. In addition, we describe the general principle of the applications and analyses built on GEMs. The purpose of this review is to introduce the application of GEMs in biological analysis and to promote its wider use by biologists. Frontiers Media S.A. 2016-01-07 /pmc/articles/PMC4703781/ /pubmed/26779040 http://dx.doi.org/10.3389/fphys.2015.00413 Text en Copyright © 2016 Zhang and Hua. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Zhang, Cheng Hua, Qiang |
| spellingShingle |
Zhang, Cheng Hua, Qiang Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| author_facet |
Zhang, Cheng Hua, Qiang |
| author_sort |
Zhang, Cheng |
| title |
Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| title_short |
Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| title_full |
Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| title_fullStr |
Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| title_full_unstemmed |
Applications of Genome-Scale Metabolic Models in Biotechnology and Systems Medicine |
| title_sort |
applications of genome-scale metabolic models in biotechnology and systems medicine |
| description |
Genome-scale metabolic models (GEMs) have become a popular tool for systems biology, and they have been used in many fields such as industrial biotechnology and systems medicine. Since more and more studies are being conducted using GEMs, they have recently received considerable attention. In this review, we introduce the basic concept of GEMs and provide an overview of their applications in biotechnology, systems medicine, and some other fields. In addition, we describe the general principle of the applications and analyses built on GEMs. The purpose of this review is to introduce the application of GEMs in biological analysis and to promote its wider use by biologists. |
| publisher |
Frontiers Media S.A. |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703781/ |
| _version_ |
1613520766351966208 |