Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences

Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences

Generating a diverse B cell immunoglobulin repertoire is essential for protection against infection. The repertoire in humans can now be comprehensively measured by high-throughput sequencing. Using hepatitis B vaccination as a model, we determined how the total immunoglobulin sequence repertoire ch...

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Bibliographic Details
Main Authors: Galson, Jacob D., Trück, Johannes, Fowler, Anna, Clutterbuck, Elizabeth A., Münz, Márton, Cerundolo, Vincenzo, Reinhard, Claudia, van der Most, Robbert, Pollard, Andrew J., Lunter, Gerton, Kelly, Dominic F.
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703725/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703725/

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