Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity

Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity

Antibodies (Abs) specific for the V3 loop of the HIV-1 gp120 envelope neutralize most tier 1 and many tier 2 viruses and are present in essentially all HIV-infected individuals as well as immunized humans and animals. Vaccine-induced V3 Abs are associated with reduced HIV infection rates in humans a...

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Bibliographic Details
Main Authors: Zolla-Pazner, Susan, Cohen, Sandra Sharpe, Boyd, David, Kong, Xiang-Peng, Seaman, Michael, Nussenzweig, Michel, Klein, Florian, Overbaugh, Julie, Totrov, Max
Format: Online
Language:English
Published: American Society for Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702699/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702699/

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