FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly

FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly

Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). FOXP3+ Tregs could regulate inflammation, but it is unclear where these cells are produced and what roles they play in human schistosomiasis. We investigated blood...

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Bibliographic Details
Main Authors: Romano, Audrey, Hou, Xunya, Sertorio, Mathieu, Dessein, Hélia, Cabantous, Sandrine, Oliveira, Pablo, Li, Jun, Oyegue, Sandrine, Arnaud, Violaine, Luo, Xinsong, Chavanieu, Martine, Mariani, Odette, Sastre, Xavier, Dombey, Anne-Marie, He, Hongbin, Li, Yuesheng, Dessein, Alain
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701139/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701139/

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