Roles of nucleic acid substrates and cofactors in the vhs protein activity of pseudorabies virus

Pseudorabies virus (PrV) belongs to the α-herpesvirinae of which human simplex virus (HSV) is the prototype virus. One of the hallmarks of HSV infection is shutoff of protein synthesis that is mediated by various viral proteins including vhs (virion host shutoff), which is encoded by the UL41 gene....

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Main Authors: Liu, Ya-Fen, Tsai, Pei-Yun, Lin, Fong-Yuan, Lin, Kuan-Hsun, Chang, Tien-Jye, Lin, Hui-Wen, Chulakasian, Songkhla, Hsu, Wei-Li
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699370/