Structure-Activity Relationship Study of the Neuritogenic Potential of the Glycan of Starfish Ganglioside LLG-3 ‡

LLG-3 is a ganglioside isolated from the starfish Linchia laevigata. To clarify the structure-activity relationship of the glycan of LLG-3 toward rat pheochromocytoma PC12 cells in the presence of nerve growth factor, a series of mono- to tetrasaccharide glycan derivatives were chemically synthesize...

Full description

Bibliographic Details
Main Authors: Yamagishi, Megumi, Hosoda-Yabe, Ritsuko, Tamai, Hideki, Konishi, Miku, Imamura, Akihiro, Ishida, Hideharu, Yabe, Tomio, Ando, Hiromune, Kiso, Makoto
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699235/