Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Genome-wide association studies of 146 plasma protein levels in 818 individuals revealed 56 genome-wide significant associations (28 novel) with 47 analytes. Loci associated with plasma levels of 39 proteins tested have been previously associated with various complex traits such as heart disease, in...

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Bibliographic Details
Main Authors: Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Del-Aguila, Jorge L., Fernandez, Maria Victoria, Carrell, David, Black, Kathleen, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Bailey, Matthew, Ridge, Perry G., Holtzman, David, Morris, John C., Bales, Kelly, Pickering, Eve H., Lee, Jin-Moo, Heitsch, Laura, Kauwe, John, Goate, Alison, Piccio, Laura, Cruchaga, Carlos
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698720/