Zearalenone Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2

Zearalenone is a mycotoxin produced by Fusarium spp. 11β-Hydroxysteroid dehydrogenases, isoforms 1 (HSD11B1) and 2 (HSD11B2), have been demonstrated to be the regulators of the local level of active glucocorticoid, which has a broad range of physiological actions. In the present study, the potency o...

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Bibliographic Details
Main Authors: Li, Linxi, Wu, Xiaolong, Guan, Hongguo, Mao, Baiping, Wang, Huang, Yuan, Xiaohuan, Chu, Yanhui, Sun, Jianliang, Ge, Ren-Shan
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698529/