Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary

Familial adenomatous polyposis (FAP) is a colorectal cancer predisposition syndrome with considerable genetic and phenotypic heterogeneity, defined by the development of multiple adenomas throughout the colorectum. FAP is caused either by monoallelic mutations in the adenomatous polyposis coli gene...

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Bibliographic Details
Main Authors: Papp, Janos, Kovacs, Marietta Eva, Matrai, Zoltan, Orosz, Enikő, Kásler, Miklós, Børresen-Dale, Anne-Lise, Olah, Edith
Format: Online
Language:English
Published: Springer Netherlands 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698287/