High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer

A growing body of evidence indicates that miRNAs may be a class of genetic elements that can either drive or suppress oncogenesis. In this study we analyzed the somatic copy number variation of 14 miRNA genes frequently found to be either over- or underexpressed in lung cancer, as well as two miRNA...

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Bibliographic Details
Main Authors: Czubak, Karol, Lewandowska, Marzena Anna, Klonowska, Katarzyna, Roszkowski, Krzysztof, Kowalewski, Janusz, Figlerowicz, Marek, Kozlowski, Piotr
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695126/