Notch signaling deregulation in multiple myeloma: A rational molecular target

Despite recent therapeutic advances, multiple myeloma (MM) is still an incurable neoplasia due to intrinsic or acquired resistance to therapy. Myeloma cell localization in the bone marrow milieu allows direct interactions between tumor cells and non-tumor bone marrow cells which promote neoplastic c...

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Bibliographic Details
Main Authors: Colombo, Michela, Galletti, Serena, Garavelli, Silvia, Platonova, Natalia, Paoli, Alessandro, Basile, Andrea, Taiana, Elisa, Neri, Antonino, Chiaramonte, Raffaella
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694956/