Immunomodulation and Disease Tolerance to Staphylococcus aureus

The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome....

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Main Authors: Li, Zhigang, Peres, Adam G., Damian, Andreea C., Madrenas, Joaquín
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693165/
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spelling pubmed-46931652016-01-06 Immunomodulation and Disease Tolerance to Staphylococcus aureus Li, Zhigang Peres, Adam G. Damian, Andreea C. Madrenas, Joaquín Review The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome. In contrast, S. aureus is also a common commensal microbe and is often part of the human nasal microbiome without causing any apparent disease. In this review, we explore the immunomodulation and disease tolerance mechanisms that promote commensalism to S. aureus. MDPI 2015-11-13 /pmc/articles/PMC4693165/ /pubmed/26580658 http://dx.doi.org/10.3390/pathogens4040793 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Li, Zhigang
Peres, Adam G.
Damian, Andreea C.
Madrenas, Joaquín
spellingShingle Li, Zhigang
Peres, Adam G.
Damian, Andreea C.
Madrenas, Joaquín
Immunomodulation and Disease Tolerance to Staphylococcus aureus
author_facet Li, Zhigang
Peres, Adam G.
Damian, Andreea C.
Madrenas, Joaquín
author_sort Li, Zhigang
title Immunomodulation and Disease Tolerance to Staphylococcus aureus
title_short Immunomodulation and Disease Tolerance to Staphylococcus aureus
title_full Immunomodulation and Disease Tolerance to Staphylococcus aureus
title_fullStr Immunomodulation and Disease Tolerance to Staphylococcus aureus
title_full_unstemmed Immunomodulation and Disease Tolerance to Staphylococcus aureus
title_sort immunomodulation and disease tolerance to staphylococcus aureus
description The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome. In contrast, S. aureus is also a common commensal microbe and is often part of the human nasal microbiome without causing any apparent disease. In this review, we explore the immunomodulation and disease tolerance mechanisms that promote commensalism to S. aureus.
publisher MDPI
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693165/
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