Immunomodulation and Disease Tolerance to Staphylococcus aureus
The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome....
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pubmed-46931652016-01-06 Immunomodulation and Disease Tolerance to Staphylococcus aureus Li, Zhigang Peres, Adam G. Damian, Andreea C. Madrenas, Joaquín Review The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome. In contrast, S. aureus is also a common commensal microbe and is often part of the human nasal microbiome without causing any apparent disease. In this review, we explore the immunomodulation and disease tolerance mechanisms that promote commensalism to S. aureus. MDPI 2015-11-13 /pmc/articles/PMC4693165/ /pubmed/26580658 http://dx.doi.org/10.3390/pathogens4040793 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
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Open Access Journal |
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Foreign Institution |
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US National Center for Biotechnology Information |
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NCBI PubMed |
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Online Access |
language |
English |
format |
Online |
author |
Li, Zhigang Peres, Adam G. Damian, Andreea C. Madrenas, Joaquín |
spellingShingle |
Li, Zhigang Peres, Adam G. Damian, Andreea C. Madrenas, Joaquín Immunomodulation and Disease Tolerance to Staphylococcus aureus |
author_facet |
Li, Zhigang Peres, Adam G. Damian, Andreea C. Madrenas, Joaquín |
author_sort |
Li, Zhigang |
title |
Immunomodulation and Disease Tolerance to Staphylococcus aureus |
title_short |
Immunomodulation and Disease Tolerance to Staphylococcus aureus |
title_full |
Immunomodulation and Disease Tolerance to Staphylococcus aureus |
title_fullStr |
Immunomodulation and Disease Tolerance to Staphylococcus aureus |
title_full_unstemmed |
Immunomodulation and Disease Tolerance to Staphylococcus aureus |
title_sort |
immunomodulation and disease tolerance to staphylococcus aureus |
description |
The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome. In contrast, S. aureus is also a common commensal microbe and is often part of the human nasal microbiome without causing any apparent disease. In this review, we explore the immunomodulation and disease tolerance mechanisms that promote commensalism to S. aureus. |
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MDPI |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693165/ |
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1613517291104763904 |