Downregulation of the Canonical WNT Signaling Pathway by TGFβ1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics

Downregulation of the Canonical WNT Signaling Pathway by TGFβ1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics

Müller glia are responsible for the retina regeneration observed in zebrafish. Although the human retina harbors Müller glia with stem cell characteristics, there is no evidence that they regenerate the retina after disease or injury. Transforming growth factor-β (TGFβ) and Wnt signaling regulate re...

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Bibliographic Details
Main Authors: Angbohang, Angshumonik, Wu, Na, Charalambous, Thalis, Eastlake, Karen, Lei, Yuan, Kim, Yung Su, Sun, Xinghuai H., Limb, G. Astrid
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692127/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692127/

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