New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies

The Amyloid Precursor Protein (APP) has been extensively studied for its role as the precursor of the β-amyloid protein (Aβ) in Alzheimer’s disease (AD). However, our understanding of the normal function of APP is still patchy. Emerging evidence indicates that a dysfunction in APP trafficking and de...

Full description

Bibliographic Details
Main Authors: Poulsen, Ebbe Toftgaard, Larsen, Agnete, Zollo, Alen, Jørgensen, Arne L., Sanggaard, Kristian W., Enghild, Jan J., Matrone, Carmela
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691124/