Influence of FcγRIIa-Expressing Cells on the Assessment of Neutralizing and Enhancing Serum Antibodies Elicited by a Live-Attenuated Tetravalent Dengue Vaccine
In vitro neutralization assays utilizing FcγRIIa-expressing cells provide evidence that serotype-specific antibody enhancement may not be a primary factor in the serotype-specific efficacy differences exhibited in the CYD-TDV trials.
| Main Authors: | , , , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Oxford University Press
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689971/ |