Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation

Phong et al. show that depending on the expression of p-Lyn, mast cell activation by antigen can result in dichotomous effects on mast cell function and signaling that can be accentuated by Tim-3 ligation.

Bibliographic Details
Main Authors: Phong, Binh L., Avery, Lyndsay, Sumpter, Tina L., Gorman, Jacob V., Watkins, Simon C., Colgan, John D., Kane, Lawrence P.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689164/