Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation

Antibody-mediated rejection (AMR) is a key limiting factor for long-term graft survival in solid organ transplantation. Human leukocyte antigen (HLA) class I (HLA I) antibodies (Abs) play a major role in the pathogenesis of AMR via their interactions with HLA molecules on vascular endothelial cells...

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Bibliographic Details
Main Authors: Zilian, Eva, Saragih, Hendry, Vijayan, Vijith, Hiller, Oliver, Figueiredo, Constanca, Aljabri, Abid, Blasczyk, Rainer, Theilmeier, Gregor, Becker, Jan Ulrich, Larmann, Jan, Immenschuh, Stephan
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686182/