Optogenetics in Mice Performing a Visual Discrimination Task: Measurement and Suppression of Retinal Activation and the Resulting Behavioral Artifact

Optogenetic techniques are used widely to perturb and interrogate neural circuits in behaving animals, but illumination can have additional effects, such as the activation of endogenous opsins in the retina. We found that illumination, delivered deep into the brain via an optical fiber, evoked a beh...

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Bibliographic Details
Main Authors: Danskin, Bethanny, Denman, Daniel, Valley, Matthew, Ollerenshaw, Douglas, Williams, Derric, Groblewski, Peter, Reid, Clay, Olsen, Shawn, Waters, Jack
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686123/