Synthesis of D-fructose-derived spirocyclic 2-substituted-2-oxazoline ribosides
The TMSOTf-mediated synthesis of β-configured spirocyclic 2-substituted-2-oxazoline ribosides was achieved using a “Ritter-like” reaction in toluene through nucleophilic addition of electron-rich nitriles to the oxacarbenium ion intermediate of 1,2;3,4-di-O-isopropylidene-β-D-psicofuranose derivativ...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685833/ |