Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient

The hepatitis C virus (HCV) is a species of diverse genotypes that infect over 170 million people worldwide, causing chronic inflammation, cirrhosis and hepatocellular carcinoma. HCV genotype 3a is common in Brazil, and it is associated with a relatively poor response to current direct-acting antivi...

Full description

Bibliographic Details
Main Authors: Provazzi, Paola J. S., Mukherjee, Sourav, Hanson, Alicia M., Nogueira, Mauricio L., Carneiro, Bruno M., Frick, David N., Rahal, Paula
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684341/