Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection

Staphylococcus aureus is capable of infecting nearly every organ in the human body. In order to infiltrate and thrive in such diverse host tissues, staphylococci must possess remarkable flexibility in both metabolic and virulence programs. To investigate the genetic requirements for bacterial survi...

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Bibliographic Details
Main Authors: Wilde, Aimee D., Snyder, Daniel J., Putnam, Nicole E., Valentino, Michael D., Hammer, Neal D., Lonergan, Zachery R., Hinger, Scott A., Aysanoa, Esar E., Blanchard, Catlyn, Dunman, Paul M., Wasserman, Gregory A., Chen, John, Shopsin, Bo, Gilmore, Michael S., Skaar, Eric P., Cassat, James E.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684308/