A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection

Enterovirus 71 (EV71), one of the major pathogens of Hand, foot and mouth disease (HFMD), results in millions of infections and hundreds of deaths each year in Southeast Asia. Biased infection and variable clinical manifestations of EV71 HFMD indicated that host genetic background played an importan...

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Bibliographic Details
Main Authors: Zou, Rongrong, Zhang, Guoliang, Li, Shaoyuan, Wang, Wenfei, Yuan, Jing, Li, Jianming, Wang, Yanrong, Lin, Yimin, Deng, Yong, Zhou, Boping, Gao, George Fu, Liu, Yingxia
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683517/