Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming
MicroRNAs (miRNAs) are important regulators of reprogramming of somatic cells into induced pluripotent stem cells (iPSCs); however, it is unclear whether miRNAs are required for reprogramming and whether miRNA activity as a whole facilitates reprogramming. Here we report on successful reprogramming...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682342/ |