Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

DNA hypomethylation in certain genes is associated with tobacco exposure but it is unknown whether these methylation changes translate into increased lung cancer risk. In an epigenome-wide study of DNA from pre-diagnostic blood samples from 132 case–control pairs in the NOWAC cohort, we observe that...

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Bibliographic Details
Main Authors: Fasanelli, Francesca, Baglietto, Laura, Ponzi, Erica, Guida, Florence, Campanella, Gianluca, Johansson, Mattias, Grankvist, Kjell, Johansson, Mikael, Assumma, Manuela Bianca, Naccarati, Alessio, Chadeau-Hyam, Marc, Ala, Ugo, Faltus, Christian, Kaaks, Rudolf, Risch, Angela, De Stavola, Bianca, Hodge, Allison, Giles, Graham G., Southey, Melissa C., Relton, Caroline L., Haycock, Philip C., Lund, Eiliv, Polidoro, Silvia, Sandanger, Torkjel M., Severi, Gianluca, Vineis, Paolo
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682166/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682166/

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