High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma

High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma

Mutations in SETD2, a histone H3 lysine trimethyltransferase, have been identified in clear cell renal cell carcinoma (ccRCC); however it is unclear if loss of SETD2 function alters the genomic distribution of histone 3 lysine 36 trimethylation (H3K36me3) in ccRCC. Furthermore, published epigenomic...

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Bibliographic Details
Main Authors: Ho, T H, Park, I Y, Zhao, H, Tong, P, Champion, M D, Yan, H, Monzon, F A, Hoang, A, Tamboli, P, Parker, A S, Joseph, R W, Qiao, W, Dykema, K, Tannir, N M, Castle, E P, Nunez-Nateras, R, Teh, B T, Wang, J, Walker, C L, Hung, M-C, Jonasch, E
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679725/

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