SKI2 mediates degradation of RISC 5′-cleavage fragments and prevents secondary siRNA production from miRNA targets in Arabidopsis

Small regulatory RNAs are fundamental in eukaryotic and prokaryotic gene regulation. In plants, an important element of post-transcriptional control is effected by 20–24 nt microRNAs (miRNAs) and short interfering RNAs (siRNAs) bound to the ARGONAUTE1 (AGO1) protein in an RNA induced silencing compl...

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Bibliographic Details
Main Authors: Branscheid, Anja, Marchais, Antonin, Schott, Gregory, Lange, Heike, Gagliardi, Dominique, Andersen, Stig Uggerhøj, Voinnet, Olivier, Brodersen, Peter
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678812/