Hormonal therapy with estradiol and drospirenone improves endothelium-dependent vasodilation in the coronary bed of ovariectomized spontaneously hypertensive rats

Drospirenone (DRSP) is a progestin with anti-aldosterone properties and it reduces blood pressure in hypertensive women. However, the effects of DRSP on endothelium-dependent coronary vasodilation have not been evaluated. This study investigated the effects of combined therapy with estrogen (E2) and...

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Bibliographic Details
Main Authors: Borgo, M.V., Claudio, E.R.G., Silva, F.B., Romero, W.G., Gouvea, S.A., Moysés, M.R., Santos, R.L., Almeida, S.A., Podratz, P.L., Graceli, J.B., Abreu, G.R.
Format: Online
Language:English
Published: Associação Brasileira de Divulgação Científica 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678653/