The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer

Reliable mouse models are key in the discovery and development of novel anticancer treatments. Non-invasive monitoring techniques such as bioluminescence imaging (BLI) are useful tools to determine tumor engraftment and evaluate tumor growth. However, the development of ascites in ovarian cancer mou...

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Bibliographic Details
Main Authors: Baert, Thaïs, Verschuere, Tina, Van Hoylandt, Anaïs, Gijsbers, Rik, Vergote, Ignace, Coosemans, An
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678634/